Portfolio Holdings Detail for ISIN IE00BDZVHG35
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Stock Name / Fund iShares Nasdaq US Biotechnology UCITS ETF USD (Dist)
Issuer Blackrock

ETF Ticker BTEE(USD) LSE
ETF Ticker BTEE.L(GBP) LSE

Holdings detail for IONS

Stock Name	Ionis Pharmaceuticals Inc
Ticker	IONS(USD) NASDAQ
TYPE	Common Stock
Country	USA
ISIN	US4622221004
LEI	549300SI4ZGLG0BLUZ92

Show aggregate IONS holdings

News associated with IONS

Ionis Pharma Reports Positive Topline Results From Pivotal Study Of Zilganersen In Alexander Disease: (RTTNews) - Ionis Pharmaceuticals, Inc. (IONS) announced Monday positive topline results from the pivotal study of zilganersen in children and adults living with Alexander disease (AxD), a rare, progressive and often fatal neurological condition with no approved disease-modifying - 2025-09-22 08:36:13
Ionis Pharmaceuticals And Sobi Say EU Approves TRYNGOLZA For Familial Chylomicronemia Syndrome: (RTTNews) - Ionis Pharmaceuticals, Inc. (IONS) and Swedish biopharmaceutical company Sobi announced Friday that TRYNGOLZA (olezarsen) has been approved in the European Union (EU) as an adjunct to diet in adult patients for the treatment of genetically confirmed familial chylomicr - 2025-09-19 08:39:56
7 Biotech Stocks Trading At 52-Week Highs - Can The Rally Continue?: (RTTNews) - Patience is a virtue - important in all aspects of life, and especially crucial when it comes to investing. As trading expert Steve Burns once said, "Much of our trading comes down to a battle between our patience and our impulses." - 2025-09-15 03:55:16
Citigroup Increases Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $84.00: Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) had its target price boosted by equities research analysts at Citigroup from $69.00 to $84.00 in a report released on Wednesday,Benzinga reports. The firm currently has a “buy” rating on the stock. Citigroup’s price target points to a potential upside of 41.53% from the stock’s previous close. A […] - 2025-09-05 05:03:17
IONS Crosses Above Average Analyst Target: In recent trading, shares of Ionis Pharmaceuticals Inc (Symbol: IONS) have crossed above the average analyst 12-month target price of $59.91, changing hands for $60.49/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra - 2025-09-04 08:06:06
Ionis Pharmaceuticals (NASDAQ:IONS) Stock Price Expected to Rise, HC Wainwright Analyst Says: Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) had its price target hoisted by investment analysts at HC Wainwright from $70.00 to $95.00 in a research note issued on Tuesday, MarketBeat Ratings reports. The brokerage presently has a “buy” rating on the stock. HC Wainwright’s price target points to a potential upside of 57.05% from the […] - 2025-09-04 04:34:50
Ionis Pharmaceuticals (NASDAQ:IONS) Sees Strong Trading Volume on Analyst Upgrade: Shares of Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Get Free Report) saw strong trading volume on Wednesday after Citigroup raised their price target on the stock from $69.00 to $84.00. Citigroup currently has a buy rating on the stock. 1,757,603 shares changed hands during trading, a decline of 5% from the previous session’s volume of 1,844,968 […] - 2025-09-04 02:20:48
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 14:33:33
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 13:44:52
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 12:52:53
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 12:27:04
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 10:14:11
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 08:10:07
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 06:59:07
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 05:15:06
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 04:43:16
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 03:40:04
Stocks Retreat as Bond Yields Climb: The S&P 500 Index ($SPX ) (SPY ) on Tuesday closed down by -0.69%, the Dow Jones Industrials Index ($DOWI ) (DIA ) closed down by -0.55%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) closed down by -0.79%. September E-mini S&P futures (ESU25 ) fell -0.65%, and September... - 2025-09-03 01:21:35
Stocks Tumble on Higher Bond Yields: The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 20:15:06
Stocks Under Pressure from Higher Bond Yields: The S&P 500 Index ($SPX ) (SPY ) today is down by -1.15%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.83%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.32%. September E-mini S&P futures (ESU25 ) are down -1.15%, and September... - 2025-09-02 17:45:25
Stocks Under Pressure from Higher Bond Yields: The S&P 500 Index ($SPX ) (SPY ) today is down by -1.15%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -0.83%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.32%. September E-mini S&P futures (ESU25 ) are down -1.15%, and September... - 2025-09-02 13:49:14
Stocks Tumble on Higher Bond Yields: The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 13:32:33
Stocks Tumble on Higher Bond Yields: The S&P 500 Index ($SPX ) (SPY ) today is down by -1.26%, the Dow Jones Industrials Index ($DOWI ) (DIA ) is down by -1.23%, and the Nasdaq 100 Index ($IUXX ) (QQQ ) is down by -1.38%. September E-mini S&P futures (ESU25 ) are down -1.25%, and September... - 2025-09-02 12:50:37
Stock Traders Buy High Volume of Call Options on Ionis Pharmaceuticals (NASDAQ:IONS): Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Get Free Report) was the recipient of unusually large options trading activity on Wednesday. Stock traders bought 2,862 call options on the stock. Thisisanincreaseofapproximately218% compared to the average volume of 899 call options. Ionis Pharmaceuticals Stock Down 0.3% Shares of IONS opened at $42.62 on Friday. The firm has a […] - 2025-08-29 02:34:43
Ionis Pharmaceuticals (NASDAQ:IONS) Price Target Raised to $49.00 at JPMorgan Chase & Co.: Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price target boosted by JPMorgan Chase & Co. from $48.00 to $49.00 in a research report report published on Monday morning,Benzinga reports. They currently have a neutral rating on the stock. A number of other equities research analysts also recently weighed in on the stock. Needham & […] - 2025-08-26 03:10:58
Citigroup Increases Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $69.00: Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective upped by Citigroup from $65.00 to $69.00 in a report released on Friday morning,Benzinga reports. Citigroup currently has a buy rating on the stock. A number of other equities analysts also recently commented on IONS. HC Wainwright raised their price objective on Ionis Pharmaceuticals from […] - 2025-08-25 05:00:49
Barclays Forecasts Strong Price Appreciation for Ionis Pharmaceuticals (NASDAQ:IONS) Stock: Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective upped by Barclays from $57.00 to $58.00 in a research report report published on Friday morning,Benzinga reports. They currently have an overweight rating on the stock. Several other research firms have also recently weighed in on IONS. JPMorgan Chase & Co. increased their price target […] - 2025-08-25 02:58:58
HC Wainwright Raises Ionis Pharmaceuticals (NASDAQ:IONS) Price Target to $70.00: Ionis Pharmaceuticals (NASDAQ:IONS – Free Report) had its price objective lifted by HC Wainwright from $65.00 to $70.00 in a report released on Friday morning,Benzinga reports. They currently have a buy rating on the stock. Other analysts also recently issued research reports about the stock. Guggenheim reduced their price target on shares of Ionis Pharmaceuticals […] - 2025-08-25 02:58:55
Ionis Pharmaceuticals (NASDAQ:IONS) Stock Rating Upgraded by Wall Street Zen: Ionis Pharmaceuticals (NASDAQ:IONS – Get Free Report) was upgraded by research analysts at Wall Street Zen from a “hold” rating to a “buy” rating in a research report issued to clients and investors on Saturday. A number of other analysts have also issued reports on IONS. Barclays raised Ionis Pharmaceuticals from an “equal weight” rating […] - 2025-08-18 04:37:05
Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) Shares Sold by Swiss National Bank: Swiss National Bank decreased its stake in Ionis Pharmaceuticals, Inc. (NASDAQ:IONS – Free Report) by 1.4% in the 1st quarter, according to the company in its most recent filing with the Securities and Exchange Commission. The institutional investor owned 275,300 shares of the company’s stock after selling 3,900 shares during the period. Swiss National Bank’s […] - 2025-08-17 05:21:00

iShares Nasdaq US Biotechnology UCITS ETF USD (Dist) IONS holdings

Date	Number of IONS Shares Held	Base Market Value of IONS Shares	Local Market Value of IONS Shares	Change in IONS Shares Held	Change in IONS Base Value	Current Price per IONS Share Held	Previous Price per IONS Share Held
2025-12-03 (Wednesday)	112,085	USD 9,173,036	USD 9,173,036	0	USD 59,405	USD 81.84	USD 81.31
2025-12-02 (Tuesday)	112,085	USD 9,113,631	USD 9,113,631	3,990	USD 250,922	USD 81.31	USD 81.99
2025-12-01 (Monday)	108,095	USD 8,862,709	USD 8,862,709	0	USD -79,990	USD 81.99	USD 82.73
2025-11-28 (Friday)	108,095	USD 8,942,699	USD 8,942,699	266	USD 25,241	USD 82.73	USD 82.7
2025-11-27 (Thursday)	107,829	USD 8,917,458	USD 8,917,458	0	USD 0	USD 82.7	USD 82.7
2025-11-26 (Wednesday)	107,829	USD 8,917,458	USD 8,917,458	798	USD 255,439	USD 82.7	USD 80.93
2025-11-25 (Tuesday)	107,031	USD 8,662,019	USD 8,662,019	1,330	USD 362,376	USD 80.93	USD 78.52
2025-11-24 (Monday)	105,701	USD 8,299,643	USD 8,299,643	266	USD 277,094	USD 78.52	USD 76.09
2025-11-21 (Friday)	105,435	USD 8,022,549	USD 8,022,549	0	USD 313,142	USD 76.09	USD 73.12
2025-11-20 (Thursday)	105,435	USD 7,709,407	USD 7,709,407	-1,064	USD -171,519	USD 73.12	USD 74
2025-11-19 (Wednesday)	106,499	USD 7,880,926	USD 7,880,926	266	USD -33,433	USD 74	USD 74.5
2025-11-18 (Tuesday)	106,233	USD 7,914,359	USD 7,914,359	1,596	USD 248,652	USD 74.5	USD 73.26
2025-11-17 (Monday)	104,637	USD 7,665,707	USD 7,665,707	532	USD 216,994	USD 73.26	USD 71.55

Share price and value of shares held is calculated on the adjusted close price of each day (row). Changes between days reflect the gain/loss of the portfolio as a result of changes in the adjusted close price and changes in the holdings

Share Trades of IONS by Blackrock for IE00BDZVHG35

Show aggregate share trades of IONS

Date Action Quantity Market High Market Low Likely Trade Price Likely Trade Value (Profit/Loss) Average Price previous trades
2025-12-02 BUY 3,990 82.680 80.000 80.268 USD 320,269 42.57
2025-11-28 BUY 266 82.950 81.670 81.798 USD 21,758 42.17
2025-11-26 BUY 798 82.905 80.750 80.965 USD 64,610 41.76
2025-11-26 BUY 798 82.905 80.750 80.965 USD 64,610 41.76
2025-11-25 BUY 1,330 81.200 78.325 78.612 USD 104,555 41.57
2025-11-24 BUY 266 78.790 76.160 76.423 USD 20,329 41.38
2025-11-20 SELL -1,064 75.362 72.500 72.786 USD -77,445 41.03 Loss of -33,784 on sale
2025-11-19 BUY 266 75.000 71.830 72.147 USD 19,191 40.86
2025-11-18 BUY 1,596 74.520 71.990 72.243 USD 115,300 40.69
2025-11-17 BUY 532 74.420 70.695 71.067 USD 37,808 40.52
2025-11-14 BUY 266 72.540 68.900 69.264 USD 18,424 40.35
2025-11-12 BUY 266 74.500 70.400 70.810 USD 18,835 40.03
2025-11-10 BUY 265 71.490 66.660 67.143 USD 17,793 39.69
2025-11-06 BUY 265 76.780 73.910 74.197 USD 19,662 39.32
2025-11-04 BUY 266 74.210 72.400 72.581 USD 19,307 38.94
2025-10-30 BUY 1,330 74.690 71.660 71.963 USD 95,711 38.36
2025-10-29 BUY 1,031 71.880 74.050 73.833 USD 76,122 38.17
2025-10-22 SELL -1,056 71.500 71.980 71.932 USD -75,960 37.19 Loss of -36,691 on sale
2025-10-20 BUY 528 73.550 73.690 73.676 USD 38,901 36.77
2025-10-17 BUY 1,319 73.090 74.020 73.927 USD 97,510 36.56
2025-10-15 BUY 2,104 72.390 73.920 73.767 USD 155,206 36.35
2025-10-03 BUY 1,834 69.150 69.250 69.240 USD 126,986 35.94
2025-10-02 BUY 262 68.400 68.410 68.409 USD 17,923 35.75
2025-09-30 BUY 524 65.420 65.550 65.537 USD 34,341 35.38
2025-09-26 BUY 524 64.090 64.490 64.450 USD 33,772 35.03
2025-09-25 BUY 524 62.970 64.070 63.960 USD 33,515 34.85
2025-09-18 BUY 274 61.740 62.520 62.442 USD 17,109 34.68
2025-09-17 BUY 825 61.170 62.100 62.007 USD 51,156 34.52
2025-07-17 SELL -550 42.170 43.300 43.187 USD -23,753 34.20 Loss of -4,941 on sale
2025-07-16 BUY 945 42.770 42.910 42.896 USD 40,537 34.15
2025-07-11 SELL -2,176 41.730 42.190 42.144 USD -91,705 33.99 Loss of -17,742 on sale
2025-07-02 BUY 14,960 43.590 43.710 43.698 USD 653,722 33.75
2025-06-25 BUY 544 40.000 40.150 40.135 USD 21,833 33.58
2025-06-20 BUY 2,389 37.410 37.520 37.509 USD 89,609 33.48
2025-06-11 BUY 528 36.190 36.980 36.901 USD 19,484 33.34
2025-06-10 BUY 528 36.840 37.600 37.524 USD 19,813 33.31
2025-06-04 SELL -264 35.110 35.840 35.767 USD -9,442 33.24 Loss of -667 on sale
2025-04-23 BUY 264 29.100 30.120 30.018 USD 7,925 33.47
2025-04-10 SELL -2,112 26.710 27.260 27.205 USD -57,457 34.00 Profit of 14,346 on sale
2025-04-08 SELL -264 25.510 28.140 27.877 USD -7,360 34.17 Profit of 1,661 on sale
2025-04-07 SELL -264 27.570 27.610 27.606 USD -7,288 34.24 Profit of 1,752 on sale
2025-04-04 SELL -1,320 27.090 28.500 28.359 USD -37,434 34.33 Profit of 7,879 on sale
2025-04-01 BUY 2,314 27.260 30.170 29.879 USD 69,140 34.48
2025-03-31 SELL -780 30.170 30.480 30.449 USD -23,750 34.53 Profit of 3,186 on sale
2025-03-21 BUY 3,911 32.910 33.620 33.549 USD 131,210 34.72
2025-03-14 SELL -3,968 32.960 33.420 33.374 USD -132,428 34.82 Profit of 5,750 on sale
2025-03-07 SELL -494 33.810 34.900 34.791 USD -17,187 34.96 Profit of 81 on sale
2025-03-04 SELL -247 32.950 33.560 33.499 USD -8,274 35.02 Profit of 375 on sale
2025-02-25 BUY 496 31.850 32.090 32.066 USD 15,905 35.26
2025-02-19 SELL -247 31.810 34.740 34.447 USD -8,508 35.49 Profit of 258 on sale
2025-02-13 BUY 741 30.350 30.950 30.890 USD 22,889 35.84
2025-02-12 BUY 247 30.840 31.560 31.488 USD 7,778 35.94
2025-02-11 BUY 988 31.580 31.610 31.607 USD 31,228 36.04
2024-12-30 SELL -2,939 34.920 35.800 35.712 USD -104,958 37.34 Profit of 4,782 on sale
2024-11-18 SELL -3,780 33.730 34.790 34.684 USD -131,106 38.89 Profit of 15,899 on sale
2024-11-08 SELL -252 39.190 39.580 39.541 USD -9,964 38.95 Loss of -149 on sale
2024-10-21 SELL -253 39.000 39.550 39.495 USD -9,992 0.00 Loss of -9,992 on sale
Market high and low price is on the date.

Date	Action	Quantity	Market High	Market Low	Likely Trade Price	Likely Trade Value (Profit/Loss)	Average Price previous trades
2025-12-02	BUY	3,990	82.680	80.000	80.268	USD 320,269	42.57
2025-11-28	BUY	266	82.950	81.670	81.798	USD 21,758	42.17
2025-11-26	BUY	798	82.905	80.750	80.965	USD 64,610	41.76
2025-11-26	BUY	798	82.905	80.750	80.965	USD 64,610	41.76
2025-11-25	BUY	1,330	81.200	78.325	78.612	USD 104,555	41.57
2025-11-24	BUY	266	78.790	76.160	76.423	USD 20,329	41.38
2025-11-20	SELL	-1,064	75.362	72.500	72.786	USD -77,445	41.03 Loss of -33,784 on sale
2025-11-19	BUY	266	75.000	71.830	72.147	USD 19,191	40.86
2025-11-18	BUY	1,596	74.520	71.990	72.243	USD 115,300	40.69
2025-11-17	BUY	532	74.420	70.695	71.067	USD 37,808	40.52
2025-11-14	BUY	266	72.540	68.900	69.264	USD 18,424	40.35
2025-11-12	BUY	266	74.500	70.400	70.810	USD 18,835	40.03
2025-11-10	BUY	265	71.490	66.660	67.143	USD 17,793	39.69
2025-11-06	BUY	265	76.780	73.910	74.197	USD 19,662	39.32
2025-11-04	BUY	266	74.210	72.400	72.581	USD 19,307	38.94
2025-10-30	BUY	1,330	74.690	71.660	71.963	USD 95,711	38.36
2025-10-29	BUY	1,031	71.880	74.050	73.833	USD 76,122	38.17
2025-10-22	SELL	-1,056	71.500	71.980	71.932	USD -75,960	37.19 Loss of -36,691 on sale
2025-10-20	BUY	528	73.550	73.690	73.676	USD 38,901	36.77
2025-10-17	BUY	1,319	73.090	74.020	73.927	USD 97,510	36.56
2025-10-15	BUY	2,104	72.390	73.920	73.767	USD 155,206	36.35
2025-10-03	BUY	1,834	69.150	69.250	69.240	USD 126,986	35.94
2025-10-02	BUY	262	68.400	68.410	68.409	USD 17,923	35.75
2025-09-30	BUY	524	65.420	65.550	65.537	USD 34,341	35.38
2025-09-26	BUY	524	64.090	64.490	64.450	USD 33,772	35.03
2025-09-25	BUY	524	62.970	64.070	63.960	USD 33,515	34.85
2025-09-18	BUY	274	61.740	62.520	62.442	USD 17,109	34.68
2025-09-17	BUY	825	61.170	62.100	62.007	USD 51,156	34.52
2025-07-17	SELL	-550	42.170	43.300	43.187	USD -23,753	34.20 Loss of -4,941 on sale
2025-07-16	BUY	945	42.770	42.910	42.896	USD 40,537	34.15
2025-07-11	SELL	-2,176	41.730	42.190	42.144	USD -91,705	33.99 Loss of -17,742 on sale
2025-07-02	BUY	14,960	43.590	43.710	43.698	USD 653,722	33.75
2025-06-25	BUY	544	40.000	40.150	40.135	USD 21,833	33.58
2025-06-20	BUY	2,389	37.410	37.520	37.509	USD 89,609	33.48
2025-06-11	BUY	528	36.190	36.980	36.901	USD 19,484	33.34
2025-06-10	BUY	528	36.840	37.600	37.524	USD 19,813	33.31
2025-06-04	SELL	-264	35.110	35.840	35.767	USD -9,442	33.24 Loss of -667 on sale
2025-04-23	BUY	264	29.100	30.120	30.018	USD 7,925	33.47
2025-04-10	SELL	-2,112	26.710	27.260	27.205	USD -57,457	34.00 Profit of 14,346 on sale
2025-04-08	SELL	-264	25.510	28.140	27.877	USD -7,360	34.17 Profit of 1,661 on sale
2025-04-07	SELL	-264	27.570	27.610	27.606	USD -7,288	34.24 Profit of 1,752 on sale
2025-04-04	SELL	-1,320	27.090	28.500	28.359	USD -37,434	34.33 Profit of 7,879 on sale
2025-04-01	BUY	2,314	27.260	30.170	29.879	USD 69,140	34.48
2025-03-31	SELL	-780	30.170	30.480	30.449	USD -23,750	34.53 Profit of 3,186 on sale
2025-03-21	BUY	3,911	32.910	33.620	33.549	USD 131,210	34.72
2025-03-14	SELL	-3,968	32.960	33.420	33.374	USD -132,428	34.82 Profit of 5,750 on sale
2025-03-07	SELL	-494	33.810	34.900	34.791	USD -17,187	34.96 Profit of 81 on sale
2025-03-04	SELL	-247	32.950	33.560	33.499	USD -8,274	35.02 Profit of 375 on sale
2025-02-25	BUY	496	31.850	32.090	32.066	USD 15,905	35.26
2025-02-19	SELL	-247	31.810	34.740	34.447	USD -8,508	35.49 Profit of 258 on sale
2025-02-13	BUY	741	30.350	30.950	30.890	USD 22,889	35.84
2025-02-12	BUY	247	30.840	31.560	31.488	USD 7,778	35.94
2025-02-11	BUY	988	31.580	31.610	31.607	USD 31,228	36.04
2024-12-30	SELL	-2,939	34.920	35.800	35.712	USD -104,958	37.34 Profit of 4,782 on sale
2024-11-18	SELL	-3,780	33.730	34.790	34.684	USD -131,106	38.89 Profit of 15,899 on sale
2024-11-08	SELL	-252	39.190	39.580	39.541	USD -9,964	38.95 Loss of -149 on sale
2024-10-21	SELL	-253	39.000	39.550	39.495	USD -9,992	0.00 Loss of -9,992 on sale

* (if shown) = market close price used not a projected price. This is used when we do not have market data available to calculate a projection

The likely trade price/value is our estimate on the likely price the trade took place at and is not the actual trade price. The likely LOSS/GAIN is our estimate. Where a profit/loss value is shown in the Likely Trade Value column, this is derived from matching trades between periods eg the most recent previous BUY is matched with the SELL for the same number of shares and the difference between the likely BUY price and likely SELL price is calculated. Where a profit or loss is shown in the Average Price of Previous Trades column, this is dervied using the likely trade price compared to the average of previous trades based on adjusted close

Shorting History of IONS

Date	Shorted Volume	Short Exempt Volume	Total Shares Traded	% Shorted
2025-09-19	217,717	7,823	943,825	23.1%
2025-09-18	336,130	3,248	634,202	53.0%
2025-09-17	238,816	3,302	589,665	40.5%
2025-09-16	278,391	5,001	657,603	42.3%
2025-09-15	467,491	6,458	854,452	54.7%
2025-09-12	363,515	7,545	614,114	59.2%
2025-09-11	401,188	11,402	693,037	57.9%
2025-09-10	588,948	19,742	863,147	68.2%
2025-09-09	1,181,812	73,035	1,940,606	60.9%
2025-09-08	583,896	16,300	960,784	60.8%
2025-09-05	721,347	59,660	1,251,123	57.7%
2025-09-04	724,802	45,112	1,541,387	47.0%
2025-09-03	2,076,447	142,991	4,309,700	48.2%
2025-09-02	4,524,907	272,259	7,686,236	58.9%
2025-08-29	252,225	110	399,461	63.1%
2025-08-28	222,625	238	400,179	55.6%
2025-08-27	385,029	566	728,944	52.8%
2025-08-26	249,224	2	969,588	25.7%
2025-08-25	361,205	100	557,389	64.8%
2025-08-22	311,576	404	771,171	40.4%
2025-08-21	409,361	21,497	673,659	60.8%
2025-08-20	481,035	6,774	795,978	60.4%
2025-08-19	541,806	81,496	869,010	62.3%
2025-08-18	256,888	12,986	522,501	49.2%
2025-08-15	213,408	327	507,649	42.0%
2025-08-14	333,496	10,831	740,989	45.0%
2025-08-13	638,521	1,320	1,526,416	41.8%
2025-08-12	135,834	604	616,870	22.0%
2025-08-11	179,950	1,191	536,293	33.6%
2025-08-08	130,707	0	509,719	25.6%
2025-08-07	181,351	4	1,011,174	17.9%
2025-08-06	367,352	22	954,394	38.5%
2025-08-05	227,713	1,636	729,729	31.2%
2025-08-04	264,699	3,930	961,837	27.5%
2025-08-01	391,598	3,027	1,051,322	37.2%
2025-07-31	956,601	10,435	1,943,115	49.2%
2025-07-30	565,332	2	1,544,806	36.6%
2025-07-29	155,330	0	519,335	29.9%
2025-07-28	192,393	2,369	530,083	36.3%
2025-07-25	146,391	1,318	319,261	45.9%
2025-07-24	115,623	124	259,044	44.6%
2025-07-23	345,762	0	687,487	50.3%
2025-07-22	180,231	0	525,158	34.3%
2025-07-21	354,692	0	590,191	60.1%
2025-07-18	194,727	46	499,181	39.0%

The data here is derived from FINRA daily shorted trade data. The Daily Short Sale Volume is the total volume of short trades that meet certain criteria on each trade date by 6 PM ET on the trade date. The detail trade data is derived from the monthly shorted trade data which will differ in aggregate. The detail trade data is derived from the transaction level data and includes ALL trades (including exempt) and the aggregation period extends beyond 6pm.

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Note: All information is provided as is without warranty and should be used for indicative purposes only. You should independently check data before making any investment decision. This information is derived from third party sources and we cannot guarantee that their data is current, accurate, complete, free from defects etc and we therefore accept no responsibility for how it may be used. We accept no liability.

Stock Name / Fund	iShares Nasdaq US Biotechnology UCITS ETF USD (Dist)
Issuer	Blackrock
ETF Ticker	BTEE(USD) LSE
ETF Ticker	BTEE.L(GBP) LSE